New Market Research: X-linked Hypophosphatemia (XLH) Market News Break Down by Driving Factors and Forecast 2027

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4 years ago

X-linked hypophosphatemia (XLH) is inherited disorder characterized by reduced or low phosphate levels due to abnormal processing in the kidneys. This results in loss of phosphate in the urine leading to softening or weakening of bones.
The disorder is usually diagnosed in children with symptoms such as bent or bowed legs, severe dental & bone pain, and short stature. This is due to mutation in the PHEX gene on the X chromosome.
The disorder is inherited in X-linked dominant manner as the gene responsible for the condition is located on the X chromosome. Also, women with X-linked hypophosphatemia (XLH) have 50% of chance to pass the disorder to her children.
High-dose calcitriol, an active form of vitamin D and supplements of phosphate are primarily used as treatment regime. Other treatments include corrective surgery, growth hormones, and dental treatment.

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Rise in expenditure on research & development activities for genetic diseases, increase in penetration of market players focusing on the development of new therapeutic treatment for rare disease and collaborative efforts between pharmaceutical companies for developing therapies for genetic disorders are expected to drive the global X-linked hypophosphatemia (XLH) market
Moreover, recent approval of drugs for X-linked hypophosphatemia (XLH) by regulatory authorities across the globe is projected to boost the growth of the market during the forecast period
In December, 2018, Ultragenyx Pharmaceutical Inc. and Kyowa Kirin Co., Ltd announced approval for Crysvita, burosumab injection by Heath Canada for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients
In February 2018, the European Commission granted marketing authorization for Crysvita allowing the drug to be marketed in 28 countries across Europe
In January 2019, Kyowa Kirin Co., Ltd submitted an application for manufacturing and marketing approval with Japan’s Ministry of Health, Labor and Welfare (MHLW) for burosumab

Based on age group, the global X-linked hypophosphatemia (XLH) market can be classified into pediatric, adults, and elderly
The pediatric segment is anticipated to gain significant share in the global X-linked hypophosphatemia (XLH) market during the forecast period, owing to increase in prevalence of genetic disorders among children, rise in emphasis on early diagnosis & treatment of disorders among children, and significant increase in availability of therapeutic options of treatment of rare disorders among children

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Based on distribution channel, the global X-linked hypophosphatemia (XLH) market can be classified into hospital pharmacies, retail pharmacies, and online pharmacies
The hospital pharmacies segment is anticipated to gain significant share in the global X-linked hypophosphatemia (XLH) market during the forecast period, owing to rise in demand for pharmaceuticals and drug supplies for children

North America is projected to account for a prominent share of the global X-linked hypophosphatemia (XLH) market during the forecast period. Growth of the X-linked hypophosphatemia (XLH) market in the region can be ascribed to the product approvals by the Food and Drug Administration (FDA) and increase in awareness about available treatment for genetic disorders.
In April 2018, the FDA approved Crysvita for the treatment of X-linked hypophosphatemia (XLH) patients in the U.S.

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Major players operating in the global X-linked hypophosphatemia (XLH) market are:

Kyowa Kirin Co., Ltd

Global X-linked Hypophosphatemia (XLH) Market, by Age Group

Global X-linked Hypophosphatemia (XLH) Market, by Distribution Channel

Global X-linked Hypophosphatemia (XLH) Market, by Region

North America
- U.S.
- Canada
Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
Asia Pacific
- China
- Japan
- India
- Australia & Zealand
- Rest of Asia Pacific
Latin America
- Brazil
- Mexico
- Rest of Latin America
Middle East & Africa
- GCC Countries
- South Africa
- Rest of Middle East & Africa